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UPSC Prelims 2010 · Environment · Pollution Files
Excessive release of the pollutant carbon monoxide (CO) into the air may produce a condition in which oxygen supply in the human body decreases. What causes this condition?
- (a) When inhaled into the human body, CO is converted into CO₂
- (b) The inhaled CO has much higher affinity for hemoglobin as compared to oxygen
- (c) The inhaled CO destroys the chemical structure of hemoglobin
- (d) The inhaled CO adversely affects the respiratory center in the brain
Show the answer and explanation
Answer: (b) The inhaled CO has much higher affinity for hemoglobin as compared to oxygen
Haemoglobin binds CO about 200–250 times more strongly than oxygen, forming carboxyhaemoglobin — less oxygen reaches the tissues.
The idea
Haemoglobin in red blood cells carries oxygen from the lungs to the body. Carbon monoxide fits the same seat on haemoglobin and holds it more than 200 times more firmly. Once it sits there, oxygen cannot. The blood is full of haemoglobin but carries little oxygen.
CO is breathed in → Binds to haemoglobin → carboxyhaemoglobin → Oxygen cannot attach → Tissues are starved of oxygen → Headache, drowsiness, death
Why the others are wrong
(a) CO is not converted to CO₂ in the body.
(c) CO doesn’t destroy haemoglobin; it occupies it.
(d) The main effect is in the blood, not the brain’s respiratory centre.
The trap
(c) sounds dramatic, but the problem is blocking, not destruction.
Also know
Carbon monoxide has no colour or smell, so the victim gets no warning. It forms when fuel burns with too little air: a coal angithi or generator in a closed room, a running car in a shut garage. Treatment is fresh air and pure oxygen.
🔒 CO + Hb → carboxyhaemoglobin (≈ 200× O₂ affinity) → hypoxia.